Get Answers Support Payroll State South Carolina(SC) Are non-profit organizations subject to payroll taxes in South Carolina? Last modified 9/23/2024 1:49:02 AM EST South Carolina makes an exception for 501(c)(3) non-profit organizations. The South Carolina Unemployment Insurance Act exempts them from paying payroll taxes, including state unemployment insurance taxes. Was this helpful? Yes No Need more help? Get in touch with our dedicated support team Contact Us (704) 684-4751 support@taxbandits.com Sign Up for a FREE TaxBandits Account! The Smart CPA Choice Register Now Already have an account? Sign in